I haven't seen any special requests for things to see and do in the area of Simcoe so I thought I would post a few to start the ball rolling and get a feel for what people would find interesting.
Simcoe itself is a small farm town with most of the fast food outlets including DQ so there shouldn't be any withdrawal symptoms for those requiring cholesterol intake. They have a Wal-mart too.
The lay of the surrounding countryside is pleasant gentle curves and hills so one shouldn't get into too much trouble. Tail of the Dragon it is not.
I'm throwing the following up for starters and will add or edit as I find more details.
Port Dover: A beach town a few miles south, known for their perch and chip restaurants. Biker friendly.
If it's on the north shore of Lake Erie and has the name "Port" it will likely have a fish and chip shop.
Canadian Warplane Heritage, Hamilton: A flying collection of military aircraft primarily from WW II when engines growled instead of whined.
Motorcycle and Military Museum, Brantford: A collection as the title says.
Haunted Houses of Hamilton: If someone wants to look for Casper I can see what's in the works.
Niagara Falls: It can be 1 1/2 hours away or much longer if one takes the back roads.
Niagara on the Lake (NOTL): A quaint little town where jay walkers step off the curb without looking.
Bell Homestead, Brantford: Worlds first phone call came from here.
Kitchener Waterloo: A twin city arrangement. Not much in the cities but it's the edge of Mennonite country if you're into buggy watching.
Railway Museum, St Thomas: There is a working line from St Thomas to Port Stanley.
Welland: See the Welland Canal as the ships lock through.
Royal Botanical Gardens, Hamilton: Large expanse of gardens, woods, greenhouses and fields.
I'll look for more to add or you can browse www.cruisethecoast.ca
Toronto is technically an hour and a half away but you start getting the feel of it a lot sooner. If anyone in interested in the CN Tower, Toronto Islands or other attractions PM me and I will try to get you info.
FWIW someone commented that the only good riding road in Toronto is the one leaving the city.
Please feel free to add or comment.