Having worked a long time for one of the world's largest ibuprofen manufacturers, you should do a web search on the recent studies published about how ibuprofen impacts men.
Around the age of 60ish something, I twisted a knee very severely, I was prescribed to use 800mg of Ibuprofen twice a day until the pain subsided.... I suppose at the time, no alerts had been noted on this issue.
not that I was concerned of that particular problem anyway.... my son had been married for many years by that time.... :grin3:
at 75 y/o now, I still use 400mg once in a while to let my muscles relax so I can get some sleep. :|